hostess (n.)

"person who receives guests," especially for pay, late 13c., from Old French oste, hoste "guest, host, hostess, landlord" (12c., Modern French hôte), from Latin hospitem (nominative hospes) "guest, stranger, sojourner, visitor (hence also 'foreigner')," also "host; one bound by ties of hospitality."

This appears to be from PIE *ghos-pot-, a compound meaning "guest-master" (compare Old Church Slavonic gospodi "lord, master," literally "lord of strangers"), from the roots *ghos-ti- "stranger, guest, host" and *poti- "powerful; lord." The etymological notion is of someone "with whom one has reciprocal duties of hospitality" [Watkins]. The biological sense of "animal or plant having a parasite" is from 1857.

fem. suffix, from French -esse, from Late Latin -issa, from Greek -issa (cognate with Old English fem. agent suffix -icge); rare in classical Greek but more common later, in diakonissa "deaconess" and other Church terms picked up by Latin.